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However, every saga has its beginning. 15 years ago, the original Despicable Me opened in theaters and started not only a license to print money, but also a new animation titan in Illumination. What was so risky back in July 2010 has become a titan franchise in 2025.
The Odds Were Once Stacked Against Despicable Me

Believe it or not, several factors in the 2010 cinema landscape seemed to indicate Despicable Me had, at best, a drastic box office ceiling for how high it could go. Prior to July 9, 2010 (the day Despicable Me opened in American theaters), only five animated family films that weren’t from Disney or DreamWorks had crossed $150+ million domestically (two of those five were Ice Age sequels). Studios had been reminded of the harsh box office realities for non-Disney/DreamWorks/Blue Sky Studios animated titles in 2006, when countless animated features opened trying to become the next Shrek.
The result was box office bombs like The Wild, The Ant Bully, Doogal, and countless more. Largely sitting out that year (save for the hand-drawn February 2006 feature Curious George) was Despicable Me distributor Universal Pictures. This studio’s modern animated track record was extremely minimal. After 1980s hits like An American Tail and The Land Before Time, Universal’s Amblimation box office duds in the ’90s turned the studio off animated family fare for eons. Was Despicable Me really going to overcome both Universal’s mixed animation track record and the limitations of non-Disney/DreamWorks animated features?
The answer to both questions turned out to be a resounding yes. Opening to $56.39 million in North America, Despicable Me rode outstanding word-of-mouth to a jaw-dropping $251.6 million domestic total. Not only did Despicable Me outgross all three DreamWorks Animation titles in 2010 (including the fourth Shrek installment), it made more cash in the US than then-recent Pixar titles like WALL-E and Ratatouille. Defying all the rules, Despicable Me proved family-friendly animated box office hits really could come from anywhere.









